![C36H39N5O8 Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl- N-(2-methyl-1-oxopropyl)- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C36H39N5O8 Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl- N-(2-methyl-1-oxopropyl)- (9CI, ACI) Picha Iliyoangaziwa](https://cdn.globalso.com/nvchem/C36H39N5O8-Guanosine.jpg)
C36H39N5O8 Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl- N-(2-methyl-1-oxopropyl)- (9CI, ACI)
| Sifa Muhimu za Kimwili | Thamani | Hali |
| Uzito wa Masi | 669.72 | - |
| Msongamano (Uliotabiriwa) | 1.35±0.1 g/cm3 | Joto: 20 ° C; Bonyeza: 760 Torr |
| pKa (Iliyotabiriwa) | 9.16±0.20 | Halijoto ya Asidi Zaidi: 25 °C |
TABASAMU za Kikanuni O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6= CC=C(OC)C=C6)C(O)C3OC
Isomeric TABASAMU
C(OC[C@H]1O[C@H]([C@H](OC)[C@@H]1O)N2C3=C(N=C2)C(=O)N=C(NC( C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC
=CC=C6
InChI
InChI=1S/C36H39N5O8/c1-21(2)32(43)39-35-38-31-28(33(44)40-35)37-20-41(31)34-30(47-5) 29(42)27(49-34)19-48-36(22-9-7-6-8-10-2 2,23-11-15-25(45-3)16-12-23)24 -13-17-26(46-4)18-14-24/h6-18,20-21,27,29-30,34,42H,19H2,1-5H3,(H2,38,39,40, 43,44)/t27-,29-,30-,34
-/m1/s1
Ufunguo wa InChi
ISQLJOGRNUQHJX-WIFIACMTSA-N
1 Jina Lingine la Dawa hii
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-N-(2-methyl-1-oxopropyl)guanosine (ACI)
| Mali zinazopatikana |
| Kibiolojia |
| Kemikali |
| Msongamano |
| Lipinski |
| Kuhusiana na Muundo |
Kibiolojia
| Mali | Thamani | Hali | Chanzo |
| Kipengele cha Mkusanyiko wa Kibiolojia | 797 | pH 1; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2030 | pH 2; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2400 | pH 3; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2450 | pH 4; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2450 | pH 5; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2450 | pH 6; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2420 | pH 7; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 2170 | pH 8; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 1070 | pH 9; Joto: 25 °C | (1) ACD |
| Kipengele cha Mkusanyiko wa Kibiolojia | 195 | pH 10; Joto: 25 °C | (1) ACD |
(1) Imekokotolewa kwa kutumia Advanced Kemia Development (ACD/Labs) Programu V11.02 (© 1994-2023 ACD/Labs)
Kemikali
| Mali | Thamani | Hali | Chanzo |
| Koc | 3020 | pH 1; Joto: 25 °C | (1) ACD |
| Koc | 7680 | pH 2; Joto: 25 °C | (1) ACD |
| Koc | 9100 | pH 3; Joto: 25 °C | (1) ACD |
| Koc | 9270 | pH 4; Joto: 25 °C | (1) ACD |
| Koc | 9290 | pH 5; Joto: 25 °C | (1) ACD |
| Koc | 9280 | pH 6; Joto: 25 °C | (1) ACD |
| Koc | 9170 | pH 7; Joto: 25 °C | (1) ACD |
| Koc | 8220 | pH 8; Joto: 25 °C | (1) ACD |
| Koc | 4050 | pH 9; Joto: 25 °C | (1) ACD |
| Koc | 737 | pH 10; Joto: 25 °C | (1) ACD |
| logD | 4.27 | pH 1; Joto: 25 °C | (1) ACD |
| logD | 4.68 | pH 2; Joto: 25 °C | (1) ACD |
| Mali | Thamani | Hali | Chanzo |
| logD | 4.75 | pH 3; Joto: 25 °C | (1) ACD |
| logD | 4.76 | pH 4; Joto: 25 °C | (1) ACD |
| logD | 4.76 | pH 5; Joto: 25 °C | (1) ACD |
| logD | 4.76 | pH 6; Joto: 25 °C | (1) ACD |
| logD | 4.76 | pH 7; Joto: 25 °C | (1) ACD |
| logD | 4.71 | pH 8; Joto: 25 °C | (1) ACD |
| logD | 4.40 | pH 9; Joto: 25 °C | (1) ACD |
| logD | 3.66 | pH 10; Joto: 25 °C | (1) ACD |
| logP | 4.763±0.722 | Joto: 25 °C | (1) ACD |
| Umumunyifu wa Ndani wa Misa | 3.1 x 10-4 g/L | Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 9.4 x 10-4 g/L | pH 1; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.7 x 10-4 g/L | pH 2; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | pH 3; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | pH 4; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | pH 5; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | pH 6; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | pH 7; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.5 x 10-4 g/L | pH 8; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 7.4 x 10-4 g/L | pH 9; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.9 x 10-3 g/L | pH 10; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Misa | 3.1 x 10-4 g/L | Maji yasio na buffered pH 6.99; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Ndani wa Molar | 4.6 x 10-7 mol/L | Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 1.4 x 10-6 mol/L | pH 1; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 5.5 x 10-7 mol/L | pH 2; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 4.7 x 10-7 mol/L | pH 3; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 4.6 x 10-7 mol/L | pH 4; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 4.6 x 10-7 mol/L | pH 5; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 4.6 x 10-7 mol/L | pH 6; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 4.6 x 10-7 mol/L | pH 7; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 5.2 x 10-7 mol/L | pH 8; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 1.1 x 10-6 mol/L | pH 9; Joto: 25 °C | (1) ACD |
| Umumunyifu wa Molar | 5.8 x 10-6 mol/L | pH 10; Joto: 25 °C | (1) ACD |
| Mali | Thamani | Hali | Chanzo |
| Umumunyifu wa Molar | 4.6 x 10-7 mol/L | Maji yasio na buffered pH 6.99; Joto: 25 °C | (1) ACD |
| Uzito wa Masi | 669.72 | ||
| pKa | 9.16±0.20 | Halijoto ya Asidi Zaidi: 25 °C | (1) ACD |
| pKa | 1.73±0.10 | Joto la Msingi Zaidi: 25 °C | (1) ACD |
(1) Imekokotolewa kwa kutumia Advanced Kemia Development (ACD/Labs) Programu V11.02 (© 1994-2023 ACD/Labs)
Msongamano
| Mali | Thamani | Hali | Chanzo |
| Msongamano | 1.35±0.1 g/cm3 | Joto: 20 ° C; Bonyeza: 760 Torr | (1) ACD |
| Kiasi cha Molar | 494.4±7.0 cm3/mol | Joto: 20 ° C; Bonyeza: 760 Torr | (1) ACD |
(1) Imekokotolewa kwa kutumia Advanced Kemia Development (ACD/Labs) Programu V11.02 (© 1994-2023 ACD/Labs)
Lipinski
| Mali | Thamani | Hali | Chanzo |
| Vifungo vinavyoweza kuzungushwa kwa Uhuru | 12 | (1) ACD | |
| H Wapokeaji | 13 | (1) ACD | |
| H Wafadhili | 3 | (1) ACD | |
| H Jumla ya Mfadhili/Mpokeaji | 16 | (1) ACD | |
| logP | 4.763±0.722 | Joto: 25 °C | (1) ACD |
| Uzito wa Masi | 669.72 |
(1) Imekokotolewa kwa kutumia Advanced Kemia Development (ACD/Labs) Programu V11.02 (© 1994-2023 ACD/Labs)
Kuhusiana na Muundo
| Mali | Thamani | Hali | Chanzo |
| Eneo la Uso wa Polar | 155 A2 | (1) ACD | |
(1) Imekokotolewa kwa kutumia Advanced Kemia Development (ACD/Labs) Programu V11.02 (© 1994-2023 ACD/Labs)
Spectra inapatikana
1H NMR
13C NMR
![C10H12N2O5 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrah ydro-3-hydroxy-2-(hydroxymethyl)- 7-methyl-, (2R,3 R,3aS,9aR)- (9CI, ACI)](https://cdn.globalso.com/nvchem/C10H12N2O5-6H-Furo-300x300.jpg)
![C48H54N7O8P Adenosine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – O-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite] (ACI)](https://cdn.globalso.com/nvchem/C48H54N7O8P-300x300.png)
![C50H60N5O10P Cytidine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O- (2-methoxyethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI)](https://cdn.globalso.com/nvchem/C50H60N5O10P-Cytidine-300x300.png)
![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI)](https://cdn.globalso.com/nvchem/118-Re36H44N2O8Si-Uridine-300x300.jpg)
![C44H53FN7O8 Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -deoxy-2′ – fluoro-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N, N-bis(1-methyl ethyl)phosphoramidite] (ACI)](https://cdn.globalso.com/nvchem/C44H53FN7O8-300x300.png)